p53 has many mechanisms of anticancer function, and plays a role in apoptosis, genomic stability and inhibition of angiogenesis. It plays an important role in cell cycle control. Defective p53 could allow abnormal cells to proliferate, resulting in cancer. As many as 50% of all human tumors contain p53 mutants. In normal cells, the p53 protein level is low. DNA damage and other stress signals may trigger the increase of p53 proteins, which have three major functions: growth arrest, DNA repair and apoptosis (cell death).
The importance of the P53 screening is to measure the level of the gene in every individuals in order to identify the susceptibility to get a cancer in future. The fact that we should adopt is by getting know the function of P53 in detail and how it involves in cancer mechanism. The P53 gene is a type of protein composed of 393 amino acids and it can be maintained by the correct diet therapy. In order to restore the function of P53 gene, one should know the alternate way and how to maintain it by diet therapy. The main objective of this molecular testing is to identify the root cause of the disease at earlier stage and improve the prognosis as well as the outcomes of cancer.